Did you know the average life span of Americans with sickle cell disease is 20 to 30 years less than those without sickle cell disease? New clinical approaches and treatments can lead to increased survival. In this 30-minute CME activity, Dr Biree Andemariam and Dr Laura De Castro explore current evidence-based approaches, review available agents, and discuss strategies to encourage clinical trial participation among patients. Join us to learn the latest information on this challenging disease.